Symbol
Name
ID

Psmb10
proteasome (prosome, macropain) subunit, beta type 10
MGI:1096380

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes	Splenomegaly
Disease(s) Associated with PSMB10	Splenomegaly
proteosome-associated autoinflammatory syndrome 5

Mouse Phenotypes

decreased T cell proliferation

athymia

increased granulocyte number

decreased B cell number

decreased NK cell number

decreased CD4-positive, alpha-beta T cell number

decreased CD8-positive, alpha-beta T cell number

decreased T cell number

decreased leukocyte cell number

abnormal CD8-positive, alpha-beta cytotoxic T cell morphology

decreased spleen red pulp amount

absent spleen white pulp

decreased immunoglobulin level

abnormal cytotoxic T cell physiology

abnormal T cell activation

Availability

Mouse Genotype

Psmb10^tm1Mgro/Psmb10^tm1Mgro

Psmb10^Tub6/Psmb10^Tub6

Psmb10^tm1Mgro/Psmb10^Tub6

Psmb10^Tub6/Psmb10⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23